Endocrine Abstracts

Introduction: The contribution of chronic hepatitis C virus (HCV) infection per se in thyroid autoimmunity and dysfunction remains controversial.Aim: To investigate the prevalence of thyroid disorders and the possible association between thyroid dysfunction and different factors in a cohort of HCV untreated patients.Material and methods: A total 1050 patients with untreated HCV infection were enrolled in this study. Thyroid functio...

A 46-year old male patient, living in Giza, father of 4, used to work as a baker. He is an ex-smoker. He has diabetes on insulin for 4 years, not hypertensive.He was diagnosed to have colonic carcinoma upon which surgical intervention was done in the form of right hemicolectomy with splenectomy and cholecystectomy. Postoperative pathology report revealed invasive moderately differentiated adenocarcinoma. He received postoperative chemotherapy, twelve sessions over the past one...

Background: Dysmetabolic iron overload syndrome (DIOS) is characterized by elevated ferritin and normal transferrin saturation level. Iron metabolism may be linked to the sympathetic overactity. DIOS is seen in 15–20% of the metabolic syndrome cases.Aim: This study aimed to test the hypothesis linking the increased baseline sympathetic drive to the hypertension seen in dysmetablolic iron overload syndrome in cases of metabolic syndrome.<p class=...

Introduction: Thiamine responsive megaloblastic anemia syndrome(TRMA), is an autosomal recessive disorder due to mutation of gene (SLC19A2) encoding thiamine transporter protein TRMA ischaracterized by a triad of anemia, diabetes mellitus, and sensorineural deafness.Case report: A 15 year old girl admitted to the ERwith diabetic ketoacidosis. She was diagnosed as neonatal diabetesat the age of 16 months and wasput on insulin therapy. Her parents arehealt...

Background: Hashimoto’s thyroiditis (HT) is considered the most common autoimmune disease and the predominant cause of hypothyroidism in iodine sufficient countries. HT may appear clinically in approximately 0.1–2% of the population.Aim: The study in hand aimed at assessing the role of thyroid ultrasonography in the diagnosis of HT patients discriminating them from other causes of hypothyroidism. A scoring system of sonographic findings was a...